What is the legal requirement for selling controlled substances for office use?

When selling controlled substances for office use, the legal requirement stipulates that a DEA 222 form is necessary for the purchase of Schedule II medications. This is in accordance with federal regulations governing the handling of controlled substances. Schedule II drugs are classified as having a high potential for abuse and have specific regulations to prevent misuse, which include the requirement of a formal order and documentation through the DEA 222 form.

In practice, this means that healthcare facilities or practitioners must submit a DEA 222 form whenever they need to order or transfer Schedule II controlled substances. This form serves not only as a means of tracking the distribution of these potent medications but also reinforces the regulatory framework aimed at preventing abuse and illegal distribution.

While certain other options mention various requirements for controlled substances, the unique requirement for Schedule II substances differentiates it from Schedule III-V, where invoices can suffice without the same level of scrutiny and formality required for Schedule II medications. Therefore, the focus on the DEA 222 form directly aligns with the legal framework established for controlled substances, making this the correct answer for the question regarding what is required for selling controlled substances for office use.